In the early 1990s, 40% of American women who had reached menopause used hormone replacement therapy (HRT) to treat disagreeable symptoms like hot flashes, sleep problems, and discomfort during intercourse. At one time, Premarin® (brand name for oral estrogen) was the most commonly prescribed drug in the U.S.
In 1993 the U.S. government invested over $600 million to study whether hormone replacement protected women from heart disease. That study, the Women’s Health Initiative (WHI), changed women’s lives for sure. But was this a change for the better? Read more